For Mayweather, after he defeated experienced fighters Juan Manuel Marquez and Shane Mosley he knocked out his last opponent Victor Ortiz in a bout that ended strangely with a kiss, hug, and Mayweather knocking out Ortiz after an apologetic embrace. Mayweather needs this win to keep profiting off of his dominance and legacy as well as the always looming possibility of a superfight with Manny Pacquiao.
This is another chance for Cotto to climb the pound for pound rankings after his crushing loss to Pacquiao and a win against Mayweather would do more than enough to warrant a rematch with Pacman. It will all depend how much of his recent performances were a mirage or were the real Cotto since his last bouts were against previously injured and old fighters; Margarito (eye), Foreman (knee), and Mayorga.
We know that Mayweather will be fighting the real Cotto. It should make for a good match up with Mayweather willing to fight more in recent bouts and Cotto fighting at a higher weight than against Pacquiao. Does Cotto have a chance? Yes and more than a puncher's chance, but the stars will still have to align just right. Mayweather should still dominate the fight, but if he has slowed down any then this may be just the right time for Cotto to have a chance to beat Money and continue to make more big money.
Floyd Mayweather vs Miguel Cotto - HBO Face Off with Max Kellerman